A single mammalian cell contains a vast mixture of distinct proteins, often to the degree of hundreds of millions, at variable concentrations. The magnitude and variety of protein types within sample micro volumes present significant difficulties for purification and isolation of proteins. Separating the desired protein from tissue, alongside undesirable proteins, represents one of the most labor-intensive processes in the protein extraction process. Yet this is not a stage that can be overlooked, as protein purity is an essential metric for success in practically every downstream application.
With a suite of advanced instrumentation and a team of experienced Ph.D. chemists, Jordi Labs is equipped to assist in protein purity analysis. Impurities can be identified via mass spectrometry or size exclusion chromatography with multiangle light scattering. Poor quality samples can cause proteins in solution to misfold and subsequently spoil. Protein purity, or lack thereof, can determine a sample’s tendency towards irreversible aggregation. However, if high molecular weight protein agglomerations are allowed to proliferate through to end-products in biopharmaceutical applications, they can pose significant health and efficacy risks.
Jordi Labs can rapidly and accurately quantify protein purity and concentration in solution using mass spectroscopy, ultraviolet-visible (UV-Vis) spectroscopy and chromatographic methods. Our protein purity services provide confidence in your isolation products, ensuring the integrity of analytical results and dosage form biopharmaceuticals.
Protein Testing with Jordi Labs
Jordi Labs specializes in protein analysis for an extensive range of biochemistry and life sciences applications. We can assist in the determination of protein purity and aggregation. If you would like more information about our unique laboratory testing services, please do not hesitate to contact a member of the team.
