UNKNOWNS into KNOWNS
The QTOF‐GCMS instrument combines well established gas phase chromatography techniques with the excellent mass accuracy of the quadrupole time‐of‐flight (QTOF) mass spectrometer. This technique excels in the identification of semi-volatile species through the application of a temperature ramp, chromatographic separation, mass selective detection and fragmentation in electron impact (EI) or chemical ionization (CI) modes. Typical mass resolution of a quadrupole mass spectrometer is 1 Da (mass accuracy in the 0.2‐3% range), while the QTOF mass spectrometer typically exhibits mass accuracy in the 1‐5 ppm range. An increase in sample sensitivity and decrease in background signal can be achieved through the application of ion specific Extracted Ion Chromatograms. Combine QTOF-GCMS and QTOF-LCMS to turn UNKNOWNS into KNOWNS and most definitively identify organic sample composition.
- Highly accurate mass assignments
- Structural elucidation
- Quantitation at Low ppb levels
- High quality MS/MS spectra
- Trace component detection
Learn more about QTOF-GCMS below:
| Title | Description | File |
|---|---|---|
| Whitepaper: Comparison of EI and CI in QTOF-GCMS | Comparison of the data obtained through electron impact (EI) and chemical ionization (CI) ion sources in QTOF-GCMS | |
| Case Study: Plasticizers by QTOF-GCMS | Identification of plasticizers by QTOF-GCMS | |
| Case Study: Case Study: Nylon Syringe Filter E&L | Investigate the extractable and leachables profile of a nylon syringe filter. |
