Protein aggregation is a common phenomenon in nature and often occurs during protein manufacturing processes, formulation and storage. For biopharmaceutical manufacturers, protein aggregation poses a key challenge in the development and storage of biologics as it has a great impact on drug efficacy and immunogenicity. Technology to monitor and detect protein aggregation is therefore very important to ensure the quality of protein-based pharmaceuticals. Here, we described a reliable SEC method to achieve this goal quantitatively.
![Image of Jordi Labs structure of the protein molecule.](https://jordilabs.com/wp-content/uploads/2019/03/Jordi-Molecule-Structure-istock-867159754-1140x400.jpg)