OVERVIEW
Medical professionals around the world have relied on PVC blood bags and infusion containers for years due to the compound’s superior performance and value.
However, today doctors and hospitals are looking for replacements for traditional PVC-infusion bags because the U.S. Environmental Protection Agency has classified DEHP, the most frequently used plasticizer in PVC, as a probable human carcinogen.
Alternatives, such as EVA, also reduce patients’ exposure to foreign chemicals leaching into the body.
The goal of this work was to compare an EVA and PVC infusion bag for their leachables profiles, that is, does the EVA bag do a better job of insuring unwanted agents don’t enter the body?
STUDY
The goal of this work was to compare an EVA and PVC infusion bag for their leachables profiles. Jordi Labs has extensive experience in extractables and leachables polymer testing, with a focus on medical devices testing.
ANALYTICAL STRATEGY
In an effort to obtain a complete understanding of the leachables profile, many analytical techniques were employed, including:
- Gravimetric Analysis
- Pyrolysis Gas Chromatography Mass Spectrometry (PYMS)
- Fourier Transform Infrared Spectroscopy (FTIR)
- Dynamic Headspace Gas Chromatography Mass Spectrometry (DHGCMS)
- Liquid Chromatography Mass Spectrometry (LCMS)
- Gas Chromatography Mass Spectrometry (GCMS)
CONCLUSIONS
The leachables found in samples EVA infusion bag and PVC infusion bag are summarized in Table 1 in the included report. The EVA infusion bag was found to show few types of leachables as compared to the PVC bag.
Read the following report to see the full analysis.
